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Use with digoxin: increase the risk of digoxin toxicity. Use with CYP3A inhibitors (apart from ritonavir): enhance the possibility of adverse reactions of alprazolam. Use with CYP3A inducers: increase the chance of diminished efficacy of Xanax.

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When tapering, reduce dosage by no more than 0.5 mg every single 3 days. Some sufferers may possibly involve a fair slower dosage reduction. See the entire prescribing information for your advised dosage in geriatric individuals, individuals with hepatic impairment, and with use with ritonavir.

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